In a recent study published in Journal of Endocrinological Investigation, researchers assessed male reproductive health three months after coronavirus disease 2019 (COVID-19) infection and found dire link between them.
According to its authors, the study identified vulnerability of the male gender in experiencing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and increased mortality.
The study said this susceptibility to disease severity is possibly due to a combination of behavioural or lifestyle patterns, aging, comorbidities specific to males, intrinsic biological variations between the genders, hormones, or genetics.
Explaining that they performed a comprehensive estimation of the male reproductive health of SARS-CoV-2 patients three months after recovery, the researchers said the study included participants with a history of SARS-CoV-2 infection diagnosed between July 2020 and January 2021 during which each participant was asked to undergo an andrological screening to estimate probable COVID-19 consequences.
Eligible participants had a history of previous COVID-19 positive nasopharyngeal swabs detected from July 2020 to January 2021, and three months had passed since the disease recovery before study enrollment among patients aged between 18 and 65 years through three months of post-recovery period during which the patients underwent a physical examination and a testicular ultrasound and provided a blood and semen sample.
The team compared the semen parameters of the participants to those of healthy controls who were recruited before the prevalence of COVID-19 between 2018 and 2019. The control participants were categorised as control group 1 (CTR1) which included healthy normozoospermic subjects with no andrological diseases and control group 2 (CTR2) which included healthy patients diagnosed with idiopathic infertility.