AN Igbo born medical doctor, Dr Chibawanye Ene, has won the 2019 Ronald L. Bittner Award on Brain Tumor Research.
Dr Ene , who is 37 years , won the award with his research work on ‘Anti-PD-L1 Immunotherapy Enhances Radiation-induced Abscopal Response in Glioblastoma’. Immunotherapy.
Source close to national light said that, Ene received the award at the 2019 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting held recently in San Diego.
According to him, statement from the Clinical Department, Applied Radiation Oncology U.S., said that, Glioblastoma’. Immunotherapy is a type of cancer treatment that helps immune system fight cancer..”The immune system, made up of white blood cells, organs and tissues of the lymph system, helps the body fight infections and other diseases.”
It stated that Immunotherapy is a type of biological therapy. Also, Glioblastoma, known as glioblastomamultiforme (GBM), is the most aggressive cancer that begins within the brain. Initially, signs and symptoms of glioblastoma are non-specific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke.
It further said that immunotherapy for glioblastoma has been largely unsuccessful in part, because molecular heterogeneity drives selective elimination of only a subset of tumor cells.
According to the statement, it appears that therapeutic success in patients would require achieving an abscopal effect, where following focused radiation therapy, non-targeted tumor cells are attacked by the immune system.
It disclosed that it is not clear how glioblastoma respond to focused radiation in terms of failure location and whether immunotherapy could amplify the immune response to tumor outside the radiation field. “The result of the study’s experiment show that radiation combined with anti PD L1 therapy induces an immunological response to unirradiatedglioblastoma.,”
The statement disclosed that, “researchers are currently optimizing other treatment combinations that could also be readily assessed in phase in human clinical trials.”